Optimizing Lentiviral Vector Transduction of Hematopoietic Stem Cells for Gene Therapy

Autologous gene therapy using lentiviral vectors (LVs) holds promise for treating monogenetic blood diseases. However, clinical applications can be limited by suboptimal hematopoietic stem cell (HSC) transduction and insufficient quantities of available vector. We recently reported gene therapy for...

Full description

Saved in:
Bibliographic Details
Published in:Gene Ther
Main Authors: Jang, Yoonjeong, Kim, Yoon-Sang, Wielgosz, Matthew M., Ferrara, Francesca, Ma, Zhijun, Condori, Jose, Palmer, Lance E., Zhao, Xiwen, Kang, Guolian, Rawlings, David J., Zhou, Sheng, Ryu, Byoung Y.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606410/
https://ncbi.nlm.nih.gov/pubmed/32341484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-020-0150-z
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items