Context-dependent perturbation of neural systems in transgenic mice expressing a cytosolic prion protein

We analyzed the relationship between pathogenic protein expression and perturbations to brain anatomy and physiology in a genetic model of prion disease. In this model, the mouse line 1D4, neuropathology is promoted by accumulation of a cytosolic form of the prion protein (cyPrP). CyPrP distribution...

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Udgivet i:Neuroimage
Main Authors: Faas, Henryk, Jackson, Walker S, Borkowski, Andrew W., Wang, Xinhe, Ma, Jiyan, Lindquist, Susan, Jasanoff, Alan
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605312/
https://ncbi.nlm.nih.gov/pubmed/19835963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2009.10.009
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