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Context dependent neuroprotective properties of prion protein (PrP)

Although it has been known for more than twenty years that an aberrant conformation of the prion protein (PrP) is the causative agent in prion diseases, the role of PrP in normal biology is undetermined. Numerous studies have suggested a protective function for PrP, including protection from ischemi...

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Detalhes bibliográficos
Main Authors: Steele, Andrew D, Zhou, Zhipeng, Jackson, Walker S, Zhu, Chunni, Auluck, Pavan, Moskowitz, Michael A, Chesselet, Marie-Francoise, Lindquist, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807698/
https://ncbi.nlm.nih.gov/pubmed/19901559
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