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Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity

Hsp90 is a molecular chaperone and important driver of stabilization and activation of several oncogenic proteins that are involved in the malignant transformation of tumor cells. Therefore, it is not surprising that Hsp90 has been reported to be a promising target for the treatment of several neopl...

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Detalhes bibliográficos
Publicado no:Future Med Chem
Main Authors: Walton-Diaz, Annerleim, Khan, Sahar, Bourboulia, Dimitra, Trepel, Jane B, Neckers, Len, Mollapour, Mehdi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605113/
https://ncbi.nlm.nih.gov/pubmed/23734688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.88
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