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Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity

Hsp90 is a molecular chaperone and important driver of stabilization and activation of several oncogenic proteins that are involved in the malignant transformation of tumor cells. Therefore, it is not surprising that Hsp90 has been reported to be a promising target for the treatment of several neopl...

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Bibliografiska uppgifter
I publikationen:Future Med Chem
Huvudupphovsmän: Walton-Diaz, Annerleim, Khan, Sahar, Bourboulia, Dimitra, Trepel, Jane B, Neckers, Len, Mollapour, Mehdi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605113/
https://ncbi.nlm.nih.gov/pubmed/23734688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.88
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