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Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity

Hsp90 is a molecular chaperone and important driver of stabilization and activation of several oncogenic proteins that are involved in the malignant transformation of tumor cells. Therefore, it is not surprising that Hsp90 has been reported to be a promising target for the treatment of several neopl...

詳細記述

保存先:
書誌詳細
出版年:Future Med Chem
主要な著者: Walton-Diaz, Annerleim, Khan, Sahar, Bourboulia, Dimitra, Trepel, Jane B, Neckers, Len, Mollapour, Mehdi
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7605113/
https://ncbi.nlm.nih.gov/pubmed/23734688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.88
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