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Flipping the substrate preference of Hazara virus ovarian tumour domain protease through structure-based mutagenesis
Nairoviruses are arthropod-borne viruses with a nearly global geographical distribution. Several are known causative agents of human disease, including Crimean–Congo hemorrhagic fever virus (CCHFV), which has a case fatality rate that can exceed 30%. Nairoviruses encode an ovarian tumour domain prot...
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| Udgivet i: | Acta Crystallogr D Struct Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7604911/ https://ncbi.nlm.nih.gov/pubmed/33135682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798320012875 |
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