Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity

Post-translational modification of host and viral proteins by ubiquitin (Ub) and Ub-like proteins, such as interferon stimulated gene product 15 (ISG15), plays a key role in response to infection. Viruses have been increasingly identified that contain proteases possessing deubiquitinase (DUB) and/or...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Dzimianski, John V., Beldon, Brianna S., Daczkowski, Courtney M., Goodwin, Octavia Y., Scholte, Florine E. M., Bergeron, Éric, Pegan, Scott D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343935/
https://ncbi.nlm.nih.gov/pubmed/30629698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007515
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