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Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers

Hepsin is a membrane-anchored, trypsin-like serine protease with prominent expression in the human liver and tumours of the prostate and ovaries. To better understand the biological functions of hepsin, we identified macromolecular substrates employing a tetrapeptide PS-SCL (positional scanning-synt...

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Autors principals: Herter, Sylvia, Piper, Derek E., Aaron, Wade, Gabriele, Timothy, Cutler, Gene, Cao, Ping, Bhatt, Ami S., Choe, Youngchool, Craik, Charles S., Walker, Nigel, Meininger, David, Hoey, Timothy, Austin, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184568/
https://ncbi.nlm.nih.gov/pubmed/15839837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041955
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