Modifying ADAMTS13 to modulate binding of pathogenic autoantibodies of patients with acquired thrombotic thrombocytopenic purpura

Antibodies that develop in patients with immune thrombotic thrombocytopenic purpura commonly target the spacer epitope R568/F592/R660/Y661/Y665 (RFRYY) of ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13). In this study we present a detailed contribution of...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Haematologica
Hlavní autoři: Graça, Nuno A. G., Ercig, Bogac, Pereira, Leydi Carolina Velásquez, Kangro, Kadri, Kaijen, Paul, Nicolaes, Gerry A. F., Veyradier, Agnès, Coppo, Paul, Vanhoorelbeke, Karen, Männik, Andres, Voorberg, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: Fondazione Ferrata Storti 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604655/
https://ncbi.nlm.nih.gov/pubmed/33131251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.226068
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky