Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers

Although outstanding progress has been made in understanding the pathophysiology of thrombotic thrombocytopenic purpura (TTP), knowledge of the immunopathogenesis of the disease is only at an early stage. Anti-ADAMTS13 auto-antibodies were shown to block proteolysis of von Willebrand factor and/or i...

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Publicado en:Haematologica
Main Authors: Hrdinová, Johana, D’Angelo, Silvia, Graça, Nuno A. G., Ercig, Bogac, Vanhoorelbeke, Karen, Veyradier, Agnès, Voorberg, Jan, Coppo, Paul
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2018
Assuntos:
Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029525/
https://ncbi.nlm.nih.gov/pubmed/29674502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.151407
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