Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers

Although outstanding progress has been made in understanding the pathophysiology of thrombotic thrombocytopenic purpura (TTP), knowledge of the immunopathogenesis of the disease is only at an early stage. Anti-ADAMTS13 auto-antibodies were shown to block proteolysis of von Willebrand factor and/or i...

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Publicado en:Haematologica
Autores principales: Hrdinová, Johana, D’Angelo, Silvia, Graça, Nuno A. G., Ercig, Bogac, Vanhoorelbeke, Karen, Veyradier, Agnès, Voorberg, Jan, Coppo, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Ferrata Storti Foundation 2018
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Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029525/
https://ncbi.nlm.nih.gov/pubmed/29674502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.151407
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