Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers

Although outstanding progress has been made in understanding the pathophysiology of thrombotic thrombocytopenic purpura (TTP), knowledge of the immunopathogenesis of the disease is only at an early stage. Anti-ADAMTS13 auto-antibodies were shown to block proteolysis of von Willebrand factor and/or i...

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Publicat a:Haematologica
Autors principals: Hrdinová, Johana, D’Angelo, Silvia, Graça, Nuno A. G., Ercig, Bogac, Vanhoorelbeke, Karen, Veyradier, Agnès, Voorberg, Jan, Coppo, Paul
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2018
Matèries:
Review Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029525/
https://ncbi.nlm.nih.gov/pubmed/29674502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2016.151407
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