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CopyDetective: Detection threshold–aware copy number variant calling in whole-exome sequencing data

BACKGROUND: Copy number variants (CNVs) are known to play an important role in the development and progression of several diseases. However, detection of CNVs with whole-exome sequencing (WES) experiments is challenging. Usually, additional experiments have to be performed. FINDINGS: We developed a...

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Detalhes bibliográficos
Publicado no:Gigascience
Main Authors: Sandmann, Sarah, Wöste, Marius, de Graaf, Aniek O, Burkhardt, Birgit, Jansen, Joop H, Dugas, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7604644/
https://ncbi.nlm.nih.gov/pubmed/33135740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giaa118
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