Nalaganje...
Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase
Jawed vertebrate adaptive immunity relies on the RAG1/RAG2 (RAG) recombinase, a domesticated transposase, for assembly of antigen receptor genes. Using an integration‐activated form of RAG1 with methionine at residue 848 and cryo‐electron microscopy, we determined structures that capture RAG engaged...
Shranjeno v:
| izdano v: | EMBO J |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7604617/ https://ncbi.nlm.nih.gov/pubmed/32945578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105857 |
| Oznake: |
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