Lataa...
Physiologically Based Pharmacokinetic Modeling Involving Nonlinear Plasma and Tissue Binding: Application to Prednisolone and Prednisone in Rats
The pharmacokinetics (PK) of prednisolone (PNL) exhibit nonlinearity related to plasma protein binding, tissue binding, metabolic interconversion with prednisone (PN), and renal elimination. Blood and 11 tissues were collected from male Wistar rats after steady-state (SS) infusion and after subcutan...
Tallennettuna:
| Julkaisussa: | J Pharmacol Exp Ther |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The American Society for Pharmacology and Experimental Therapeutics
2020
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7604337/ https://ncbi.nlm.nih.gov/pubmed/32883831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000191 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|