Efficacy of HDAC Inhibitors Belinostat and Panobinostat against Cisplatin-Sensitive and Cisplatin-Resistant Testicular Germ Cell Tumors

SIMPLE SUMMARY: There is a need for novel treatment options for patients with testicular germ cell tumors, especially for those that are resistant to standard chemotherapy, who show poor prognosis. In this work, we test two compounds that inhibit epigenetic enzymes called histone deacetylases—belino...

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Lobo, João, Guimarães-Teixeira, Catarina, Barros-Silva, Daniela, Miranda-Gonçalves, Vera, Camilo, Vânia, Guimarães, Rita, Cantante, Mariana, Braga, Isaac, Maurício, Joaquina, Oing, Christoph, Honecker, Friedemann, Nettersheim, Daniel, Looijenga, Leendert H. J., Henrique, Rui, Jerónimo, Carmen
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601457/
https://ncbi.nlm.nih.gov/pubmed/33050470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12102903
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