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Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription

Metformin, which is suggested to have anti-cancer effects, activates KDM2A to reduce rRNA transcription and proliferation of cancer cells. Thus, the specific activation of KDM2A may be applicable to the treatment of cancers. In this study, we screened a food-additive compound library to identify com...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cells
Prif Awduron: Tanaka, Yuji, Obinata, Hideru, Konishi, Akimitsu, Yamagiwa, Noriyuki, Tsuneoka, Makoto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601038/
https://ncbi.nlm.nih.gov/pubmed/33050392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102266
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