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Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription

Metformin, which is suggested to have anti-cancer effects, activates KDM2A to reduce rRNA transcription and proliferation of cancer cells. Thus, the specific activation of KDM2A may be applicable to the treatment of cancers. In this study, we screened a food-additive compound library to identify com...

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Библиографические подробности
Опубликовано в: :Cells
Главные авторы: Tanaka, Yuji, Obinata, Hideru, Konishi, Akimitsu, Yamagiwa, Noriyuki, Tsuneoka, Makoto
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601038/
https://ncbi.nlm.nih.gov/pubmed/33050392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102266
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