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Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription

Metformin, which is suggested to have anti-cancer effects, activates KDM2A to reduce rRNA transcription and proliferation of cancer cells. Thus, the specific activation of KDM2A may be applicable to the treatment of cancers. In this study, we screened a food-additive compound library to identify com...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cells
Päätekijät: Tanaka, Yuji, Obinata, Hideru, Konishi, Akimitsu, Yamagiwa, Noriyuki, Tsuneoka, Makoto
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601038/
https://ncbi.nlm.nih.gov/pubmed/33050392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102266
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