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Production of ROS by Gallic Acid Activates KDM2A to Reduce rRNA Transcription

Metformin, which is suggested to have anti-cancer effects, activates KDM2A to reduce rRNA transcription and proliferation of cancer cells. Thus, the specific activation of KDM2A may be applicable to the treatment of cancers. In this study, we screened a food-additive compound library to identify com...

詳細記述

保存先:
書誌詳細
出版年:Cells
主要な著者: Tanaka, Yuji, Obinata, Hideru, Konishi, Akimitsu, Yamagiwa, Noriyuki, Tsuneoka, Makoto
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7601038/
https://ncbi.nlm.nih.gov/pubmed/33050392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102266
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