Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice

Previously, we used a lentiviral vector to deliver furin-cleavable human insulin (INS-FUR) to the livers in several animal models of diabetes using intervallic infusion in full flow occlusion (FFO), with resultant reversal of diabetes, restoration of glucose tolerance and pancreatic transdifferentia...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cells
Päätekijät: La, Que T., Ren, Binhai, Logan, Grant J., Cunningham, Sharon C., Khandekar, Neeta, Nassif, Najah T., O’Brien, Bronwyn A., Alexander, Ian E., Simpson, Ann M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7600325/
https://ncbi.nlm.nih.gov/pubmed/33023100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9102227
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