Pancreatic Transdifferentiation and Glucose-Regulated Production of Human Insulin in the H4IIE Rat Liver Cell Line

Due to the limitations of current treatment regimes, gene therapy is a promising strategy being explored to correct blood glucose concentrations in diabetic patients. In the current study, we used a retroviral vector to deliver either the human insulin gene alone, the rat NeuroD1 gene alone, or the...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ren, Binhai, Tao, Chang, Swan, Margaret Anne, Joachim, Nichole, Martiniello-Wilks, Rosetta, Nassif, Najah T., O’Brien, Bronwyn A., Simpson, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848990/
https://ncbi.nlm.nih.gov/pubmed/27070593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040534
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