Reversal of diabetes following transplantation of an insulin-secreting human liver cell line: Melligen cells

As an alternative to the transplantation of islets, a human liver cell line has been genetically engineered to reverse type 1 diabetes (TID). The initial liver cell line (Huh7ins) commenced secretion of insulin in response to a glucose concentration of 2.5 mmol/l. After transfection of the Huh7ins c...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Lawandi, Janet, Tao, Chang, Ren, Binhai, Williams, Paul, Ling, Dora, Swan, M Anne, Nassif, Najah T, Torpy, Fraser R, O’Brien, Bronwyn A, Simpson, Ann M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445011/
https://ncbi.nlm.nih.gov/pubmed/26029722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.11
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