Ex Vivo Expansion of Murine MSC Impairs Transcription Factor-Induced Differentiation into Pancreatic β-Cells

Combinatorial gene and cell therapy as a means of generating surrogate β-cells has been investigated for the treatment of type 1 diabetes (T1D) for a number of years with varying success. One of the limitations of current cell therapies for T1D is the inability to generate sufficient quantities of f...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Gerace, Dario, Martiniello-Wilks, Rosetta, Habib, Rosaline, Ren, Binhai, Nassif, Najah Therese, O'Brien, Bronwyn Anne, Simpson, Ann Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431458/
https://ncbi.nlm.nih.gov/pubmed/30956666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1395301
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