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CRISPR-targeted genome editing of mesenchymal stem cell-derived therapies for type 1 diabetes: a path to clinical success?

Due to their ease of isolation, differentiation capabilities, and immunomodulatory properties, the therapeutic potential of mesenchymal stem cells (MSCs) has been assessed in numerous pre-clinical and clinical settings. Currently, whole pancreas or islet transplantation is the only cure for people w...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Gerace, Dario, Martiniello-Wilks, Rosetta, Nassif, Najah Therese, Lal, Sara, Steptoe, Raymond, Simpson, Ann Margaret
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345178/
https://ncbi.nlm.nih.gov/pubmed/28279194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0511-8
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