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Delivering multiple gene products in the brain from a single adeno-associated virus vector

For certain gene therapy applications, the simultaneous delivery of multiple genes would allow for novel therapies. In the case of adeno-associated virus (AAV) vectors, the limited packaging capacity greatly restricts current methods of carrying multiple transgene cassettes. To address this issue, a...

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Hlavní autoři: Foti, SB, Samulski, RJ, McCown, TJ
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786958/
https://ncbi.nlm.nih.gov/pubmed/19727140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.106
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