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Adeno-associated virus-mediated expression and constitutive secretion of NPY or NPY13-36 suppresses seizure activity in vivo

Neuropeptide Y (NPY) is a 36-amino-acid peptide that attenuates seizure activity following direct infusion or adeno-associated virus (AAV)-mediated expression in the central nervous system. However, NPY activates all NPY receptor subtypes, potentially causing unwanted side effects. NPY13-36 is a C-t...

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Bibliografische gegevens
Hoofdauteurs: Foti, S, Haberman, RP, Samulski, RJ, McCown, TJ
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557464/
https://ncbi.nlm.nih.gov/pubmed/17713567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3303013
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