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Identification of Hybrid Insulin Peptides (HIPs) in Mouse and Human Islets by Mass Spectrometry

We recently discovered hybrid insulin peptides (HIPs) as a novel class of post-translationally modified peptides in murine-derived beta cell tumors, and we demonstrated that these molecules are autoantigens in type 1 diabetes (T1D). A HIP consists of an insulin fragment linked to another secretory g...

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Xehetasun bibliografikoak
Argitaratua izan da:J Proteome Res
Egile Nagusiak: Wiles, T. Aaron, Powell, Roger, Michel, Cole Robert, Beard, K. Scott, Hohenstein, Anita, Bradley, Brenda, Reisdorph, Nichole, Haskins, Kathryn, Delong, Thomas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7597855/
https://ncbi.nlm.nih.gov/pubmed/30585061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00875
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