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Identification of Hybrid Insulin Peptides (HIPs) in Mouse and Human Islets by Mass Spectrometry
We recently discovered hybrid insulin peptides (HIPs) as a novel class of post-translationally modified peptides in murine-derived beta cell tumors, and we demonstrated that these molecules are autoantigens in type 1 diabetes (T1D). A HIP consists of an insulin fragment linked to another secretory g...
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| Publicat a: | J Proteome Res |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7597855/ https://ncbi.nlm.nih.gov/pubmed/30585061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00875 |
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