Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

Melanoma susceptibility differs significantly in male versus female populations. Low levels of androgen receptor (AR) in melanocytes of the two sexes are accompanied by heterogeneous expression at various stages of the disease. Irrespective of expression levels, genetic and pharmacological suppressi...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Ma, Min, Ghosh, Soumitra, Tavernari, Daniele, Katarkar, Atul, Clocchiatti, Andrea, Mazzeo, Luigi, Samarkina, Anastasia, Epiney, Justine, Yu, Yi-Ru, Ho, Ping-Chih, Levesque, Mitchell P., Özdemir, Berna C., Ciriello, Giovanni, Dummer, Reinhard, Dotto, G. Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596884/
https://ncbi.nlm.nih.gov/pubmed/33112375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201137
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