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Sustained androgen receptor signaling is a determinant of melanoma cell growth potential and tumorigenesis

Melanoma susceptibility differs significantly in male versus female populations. Low levels of androgen receptor (AR) in melanocytes of the two sexes are accompanied by heterogeneous expression at various stages of the disease. Irrespective of expression levels, genetic and pharmacological suppressi...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Ma, Min, Ghosh, Soumitra, Tavernari, Daniele, Katarkar, Atul, Clocchiatti, Andrea, Mazzeo, Luigi, Samarkina, Anastasia, Epiney, Justine, Yu, Yi-Ru, Ho, Ping-Chih, Levesque, Mitchell P., Özdemir, Berna C., Ciriello, Giovanni, Dummer, Reinhard, Dotto, G. Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596884/
https://ncbi.nlm.nih.gov/pubmed/33112375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201137
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