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Comparison of computational methods for the identification of topologically associating domains

BACKGROUND: Chromatin folding gives rise to structural elements among which are clusters of densely interacting DNA regions termed topologically associating domains (TADs). TADs have been characterized across multiple species, tissue types, and differentiation stages, sometimes in association with r...

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Publicat a:Genome Biol
Autors principals: Zufferey, Marie, Tavernari, Daniele, Oricchio, Elisa, Ciriello, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288901/
https://ncbi.nlm.nih.gov/pubmed/30526631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1596-9
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