Carregant...

Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D(2) Receptor (D(2)R) Biased Agonism

The development of bivalent ligands has attracted interest as a way to potentially improve the selectivity and/or affinity for a specific receptor subtype. The ability to bind two distinct receptor binding sites simultaneously can allow the selective activation of specific G-protein dependent or β-a...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Med Chem
Autors principals: Bonifazi, Alessandro, Yano, Hideaki, Ellenberger, Michael P., Muller, Ludovic, Kumar, Vivek, Zou, Mu-Fa, Cai, Ning Sheng, Guerrero, Adrian M., Woods, Amina S., Shi, Lei, Newman, Amy Hauck
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7594663/
https://ncbi.nlm.nih.gov/pubmed/28300398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01875
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!