Novel and Potent Dopamine D(2) Receptor Go-Protein Biased Agonists

[Image: see text] The discovery of functionally biased and physiologically beneficial ligands directed toward G-protein coupled receptors (GPCRs) has provided the impetus to design dopamine D(2) receptor (D(2)R) targeted molecules that may be therapeutically advantageous for the treatment of certain...

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Udgivet i:ACS Pharmacol Transl Sci
Main Authors: Bonifazi, Alessandro, Yano, Hideaki, Guerrero, Adrian M., Kumar, Vivek, Hoffman, Alexander F., Lupica, Carl R., Shi, Lei, Newman, Amy Hauck
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2019
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371206/
https://ncbi.nlm.nih.gov/pubmed/30775693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.8b00060
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