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Evidence for a stereoselective mechanism for bitopic activity by extended-length antagonists of the D(3) dopamine receptor
The D3 dopamine receptor (D3R) has been suggested as a drug target for the treatment of a number of neuropsychiatric disorders, including substance use disorders (SUD). Many D3R-selective antagonists are bivalent in nature in that they engage two distinct sites on the receptor – a primary pharmacoph...
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| Publicado no: | ACS Chem Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8262072/ https://ncbi.nlm.nih.gov/pubmed/32969645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.0c00425 |
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