Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

Immunotherapies have revolutionized cancer treatment. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some cancers. However, the majority of treated patients do not respond. Understanding immune mechanisms that underlie responsiveness to ICT will help...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Kidman, Joel, Principe, Nicola, Watson, Mark, Lassmann, Timo, Holt, Robert A., Nowak, Anna K., Lesterhuis, Willem Joost, Lake, Richard A., Chee, Jonathan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591700/
https://ncbi.nlm.nih.gov/pubmed/33163002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.587014
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