Tumor Infiltrating Effector Memory Antigen-Specific CD8(+) T Cells Predict Response to Immune Checkpoint Therapy

Immune checkpoint therapy (ICT) results in durable responses in individuals with some cancers, but not all patients respond to treatment. ICT improves CD8(+) cytotoxic T lymphocyte (CTL) function, but changes in tumor antigen-specific CTLs post-ICT that correlate with successful responses have not b...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Principe, Nicola, Kidman, Joel, Goh, Siting, Tilsed, Caitlin M., Fisher, Scott A., Fear, Vanessa S., Forbes, Catherine A., Zemek, Rachael M., Chopra, Abha, Watson, Mark, Dick, Ian M., Boon, Louis, Holt, Robert A., Lake, Richard A., Nowak, Anna K., Lesterhuis, Willem Joost, McDonnell, Alison M., Chee, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688517/
https://ncbi.nlm.nih.gov/pubmed/33262762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.584423
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