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Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

Immunotherapies have revolutionized cancer treatment. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some cancers. However, the majority of treated patients do not respond. Understanding immune mechanisms that underlie responsiveness to ICT will help...

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Pubblicato in:Front Immunol
Autori principali: Kidman, Joel, Principe, Nicola, Watson, Mark, Lassmann, Timo, Holt, Robert A., Nowak, Anna K., Lesterhuis, Willem Joost, Lake, Richard A., Chee, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591700/
https://ncbi.nlm.nih.gov/pubmed/33163002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.587014
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