Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

Immunotherapies have revolutionized cancer treatment. In particular, immune checkpoint therapy (ICT) leads to durable responses in some patients with some cancers. However, the majority of treated patients do not respond. Understanding immune mechanisms that underlie responsiveness to ICT will help...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kidman, Joel, Principe, Nicola, Watson, Mark, Lassmann, Timo, Holt, Robert A., Nowak, Anna K., Lesterhuis, Willem Joost, Lake, Richard A., Chee, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7591700/
https://ncbi.nlm.nih.gov/pubmed/33163002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.587014
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