Detection of Active Granzyme A in NK92 Cells with Fluorescent Activity-Based Probe

[Image: see text] Cytotoxic T-lymphocytes (CTLs) and natural killer cells (NKs) kill compromised cells to defend against tumor and viral infections. Both effector cell types use multiple strategies to induce target cell death including Fas/CD95 activation and the release of perforin and a group of l...

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Publicado en:J Med Chem
Main Authors: Kołt, Sonia, Janiszewski, Tomasz, Kaiserman, Dion, Modrzycka, Sylwia, Snipas, Scott J., Salvesen, Guy, Dra̧g, Marcin, Bird, Phillip I., Kasperkiewicz, Paulina
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590976/
https://ncbi.nlm.nih.gov/pubmed/32142286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b02042
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