Noninvasive optical detection of granzyme B from natural killer cells with enzyme-activated fluorogenic probes

Natural killer (NK) cells are key innate immunity effectors that combat viral infections and control several cancer types. For their immune function, human NK cells rely largely on five different cytotoxic proteases, called granzymes (A/B/H/K/M). Granzyme B (GrB) initiates at least three distinct ce...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Principais autores: Janiszewski, Tomasz, Kołt, Sonia, Kaiserman, Dion, Snipas, Scott J., Li, Shuang, Kulbacka, Julita, Saczko, Jolanta, Bovenschen, Niels, Salvesen, Guy, Drąg, Marcin, Bird, Phillip I., Kasperkiewicz, Paulina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Methods and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363135/
https://ncbi.nlm.nih.gov/pubmed/32439802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013204
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