Extracellular tyrosyl‐tRNA synthetase cleaved by plasma proteinases and stored in platelet α‐granules: Potential role in monocyte activation

BACKGROUND: Tyrosyl‐tRNA synthetase (YRS) belongs to the family of enzymes that catalyzes the tRNA aminoacylation reaction for protein synthesis, and it has been recently shown to exert noncanonical functions. Although database results indicate extremely low levels of YRS mRNA in platelets, YRS prot...

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Dades bibliogràfiques
Publicat a:Res Pract Thromb Haemost
Autors principals: Won, Eric, Morodomi, Yosuke, Kanaji, Sachiko, Shapiro, Ryan, Vo, My‐Nuong, Orje, Jennifer N., Thornburg, Courtney D., Yang, Xiang‐Lei, Ruggeri, Zaverio M., Schimmel, Paul, Kanaji, Taisuke
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Original Articles ‐ Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590329/
https://ncbi.nlm.nih.gov/pubmed/33134783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12429
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