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Mechanisms of anti-GPIbα antibody–induced thrombocytopenia in mice

Immune thrombocytopenia (ITP) is an acquired bleeding disorder characterized by antibody-mediated platelet destruction. Different mechanisms have been suggested to explain accelerated platelet clearance and impaired thrombopoiesis, but the pathophysiology of ITP has yet to be fully delineated. In th...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Morodomi, Yosuke, Kanaji, Sachiko, Won, Eric, Ruggeri, Zaverio M., Kanaji, Taisuke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7316218/
https://ncbi.nlm.nih.gov/pubmed/32157300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003770
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