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GPIbα regulates platelet size by controlling the subcellular localization of filamin
Interaction between the cytoplasmic domain of GPIbα with its cytoskeletal binding partner, filamin, is a major determinant of platelet size, and deficiency of either protein results in macrothrombocytopenia. To clarify the mechanism by which GPIbα-filamin interactions regulate platelet production, w...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3327465/ https://ncbi.nlm.nih.gov/pubmed/22174152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-376566 |
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