Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia

Sitosterolemia is a rare, autosomal recessive disease caused by mutations in the adenosine triphosphate-binding cassette transporter genes ABCG5 or ABCG8 that result in accumulation of xenosterols in the body. Clinical manifestations include tendon xanthomas, premature coronary artery disease, hemol...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kanaji, Taisuke, Kanaji, Sachiko, Montgomery, Robert R., Patel, Shailendra B., Newman, Peter J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2013
Pynciau:
Platelets and Thrombopoiesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795464/
https://ncbi.nlm.nih.gov/pubmed/23926302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-06-510461
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