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Abnormal megakaryocyte development and platelet function in Nbeal2(−/−) mice
Gray platelet syndrome (GPS) is an inherited bleeding disorder associated with macrothrombocytopenia and α-granule-deficient platelets. GPS has been linked to loss of function mutations in NEABL2 (neurobeachin-like 2), and we describe here a murine GPS model, the Nbeal2(−/−) mouse. As in GPS, Nbeal2...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3953091/ https://ncbi.nlm.nih.gov/pubmed/23861251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-04-499491 |
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