Dynamin 2–dependent endocytosis is required for normal megakaryocyte development in mice

Dynamins are highly conserved large GTPases (enzymes that hydrolyze guanosine triphosphate) involved in endocytosis and vesicle transport, and mutations in the ubiquitous and housekeeping dynamin 2 (DNM2) have been associated with thrombocytopenia in humans. To determine the role of DNM2 in thrombop...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Bender, Markus, Giannini, Silvia, Grozovsky, Renata, Jönsson, Terese, Christensen, Hilary, Pluthero, Fred G., Ko, Amy, Mullally, Ann, Kahr, Walter H. A., Hoffmeister, Karin M., Falet, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319232/
https://ncbi.nlm.nih.gov/pubmed/25468568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-587857
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