The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet α-granule biogenesis

Patients with platelet α or dense δ-granule defects have bleeding problems. Although several proteins are known to be required for δ-granule development, less is known about α-granule biogenesis. Our previous work showed that the BEACH protein NBEAL2 and the Sec1/Munc18 protein VPS33B are required f...

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Main Authors: Urban, Denisa, Li, Ling, Christensen, Hilary, Pluthero, Fred G., Chen, Shao Zun, Puhacz, Michael, Garg, Parvesh M., Lanka, Kiran K., Cummings, James J., Kramer, Helmut, Wasmuth, James D., Parkinson, John, Kahr, Walter H. A.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2012
主題:
Platelets and Thrombopoiesis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538988/
https://ncbi.nlm.nih.gov/pubmed/23002115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-431205
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