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Mechanism of platelet α-granule biogenesis: study of cargo transport and the VPS33B-VPS16B complex in a model system

Platelet α-granules play important roles in platelet function. They contain hundreds of proteins that are synthesized by the megakaryocyte or taken up by endocytosis. The trafficking pathways that mediate platelet α-granule biogenesis are incompletely understood, especially with regard to cargo synt...

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Bibliographic Details
Published in:Blood Adv
Main Authors: Ambrosio, Andrea L., Di Pietro, Santiago M.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6737417/
https://ncbi.nlm.nih.gov/pubmed/31501156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018028969
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