Extracellular tyrosyl‐tRNA synthetase cleaved by plasma proteinases and stored in platelet α‐granules: Potential role in monocyte activation

BACKGROUND: Tyrosyl‐tRNA synthetase (YRS) belongs to the family of enzymes that catalyzes the tRNA aminoacylation reaction for protein synthesis, and it has been recently shown to exert noncanonical functions. Although database results indicate extremely low levels of YRS mRNA in platelets, YRS prot...

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Опубликовано в: :Res Pract Thromb Haemost
Главные авторы: Won, Eric, Morodomi, Yosuke, Kanaji, Sachiko, Shapiro, Ryan, Vo, My‐Nuong, Orje, Jennifer N., Thornburg, Courtney D., Yang, Xiang‐Lei, Ruggeri, Zaverio M., Schimmel, Paul, Kanaji, Taisuke
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Original Articles ‐ Hemostasis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7590329/
https://ncbi.nlm.nih.gov/pubmed/33134783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12429
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