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Adeno-Associated Virus (AAV-DJ)—Cryo-EM Structure at 1.56 Å Resolution

Adeno-associated virus is the leading viral vector for gene therapy. AAV-DJ is a recombinant variant developed for tropism to the liver. The AAV-DJ structure has been determined to 1.56 Å resolution through cryo-electron microscopy (cryo-EM). Only apoferritin is reported in preprints at 1.6 Å or hig...

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Bibliographic Details
Published in:Viruses
Main Authors: Xie, Qing, Yoshioka, Craig K., Chapman, Michael S.
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589773/
https://ncbi.nlm.nih.gov/pubmed/33092282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12101194
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