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The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy

The structure of the adeno-associated virus (AAV-2) has been determined to 3-Å resolution by x-ray crystallography. AAV is being developed as a vector for gene therapy to treat diseases including hemophilia, cancer, and cystic fibrosis. As in the distantly related autonomous parvoviruses, the capsid...

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Detalhes bibliográficos
Main Authors: Xie, Qing, Bu, Weishu, Bhatia, Smita, Hare, Joan, Somasundaram, Thayumanasamy, Azzi, Arezki, Chapman, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124927/
https://ncbi.nlm.nih.gov/pubmed/12136130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162250899
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