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The structure of adeno-associated virus serotype 3B (AAV-3B): Insights into receptor binding and immune evasion
Adeno-associated viruses (AAVs) are leading candidate vectors for human gene therapy. AAV serotypes have broad cellular tropism and use a variety of cellular receptors. AAV serotype 3 binds to heparan sulfate proteoglycan prior to cell entry and is serologically distinct from other serotypes. The ca...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885149/ https://ncbi.nlm.nih.gov/pubmed/20444480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.03.027 |
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