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The structure of adeno-associated virus serotype 3B (AAV-3B): Insights into receptor binding and immune evasion

Adeno-associated viruses (AAVs) are leading candidate vectors for human gene therapy. AAV serotypes have broad cellular tropism and use a variety of cellular receptors. AAV serotype 3 binds to heparan sulfate proteoglycan prior to cell entry and is serologically distinct from other serotypes. The ca...

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Bibliografske podrobnosti
Main Authors: Lerch, Thomas F., Xie, Qing, Chapman, Michael S.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885149/
https://ncbi.nlm.nih.gov/pubmed/20444480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.03.027
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